A man was seriously injured in a fire that destroyed a Land O' Lakes home, according to Pasco County Fire Rescue.

Firefighters were called to the home on Drexel Road at about 2:11 a.m. Sunday.

A man who was inside the home was able to escape, authorities said. He was taken to a hospital with life-threatening injuries.

About 50 firefighters battled the two-alarm fire.

The house was deemed "a total loss," officials said.

No firefighters were injured.