One man was killed and two others were injured Thursday in a wrong-way crash on U.S. 41 in Pasco County.

The crash happened at 1:16 p.m. on U.S. 41 near Sunterra Drive.

According to the Florida Highway Patrol, Mary Roden, 38, of Spring Hill, was driving south in the northbound lanes for unknown reasons.

At the same time, Brian Scott Clukie, 40, of Tampa, was driving north in the same lanes.

Investigators said Roden's Chevrolet collided head-on with Clukie's Chevrolet.

Roden and her husband, Christopher Shawn Roden, 39, were taken to Regional Medical Center Bayonet Point in critical condition. Christopher Roden later succumbed to his injuries.

Clukie was also taken to the same hospital with serious injuries.

U.S. 41 was closed for nearly two hours during the investigation.