Sen. Jeff Sessions was confirmed as the U.S. Attorney General Wednesday after another all-night debate by Democrats who fought the nomination.

Sessions, a Republican from Alabama, was an early supporter of President Donald Trump and is considered one of the most conservative in the U.S. Senate. He has taken a hard line on illegal immigration. He has also pledge to crack down on gun violence and “the scourge of radical Islamic terrorism.”

The final vote was 52-47. Among Democrats, only Sen. Joe Manchin of West Virginia voted for Sessions.

Republicans called him tough, but honest but fair and a good colleague.

However, Democrats question whether Sessions is too close to the president and will be able to act independently as his office is allowed in cases where Trump may have overstepped his bounds.

Democrats also worry Sessions is too weak on civil rights, and particularly voting rights.

Sen. Bill Nelson, D-Florida, took to the floor Wednesday to voice his concern that Sessions will not fight efforts to block voting rights in Florida.

Nelson voted against Sessions’ confirmation.

Sen. Marco Rubio, R-Florida, voted for Sessions Wednesday. He used his time on the floor of the Senate to talk about Russia’s human rights violations and growing presence in the world.

"I appreciate the friendship from my colleagues -- even those who, many of them who didn't feel able to vote for me," Sessions said to reporters. "They were cordial, and so we continue to have good relations and will continue to do the best I can."

Session's nomination is one of several that Democrats have fought because of concerns. It's caused uncharacteristic tension, even for a chamber that's been more and more polarized in recent years. 

On Tuesday, Democrats held up the nomination with speeches. Republicans invoked a Senate rule to stop Sen. Elizabeth Warren, D-Massachusetts, from speaking against Sessions. Warren was reading a 1986 letter from civil rights activist Coretta Scott King opposing Sessions for a federal judgeship. McConnell said Warren impugned a senator (Sessions).

The move galavanized liberals across social media, who have used Senate Majority Leader Mitch McConnell's words in rebuking Warren as a rallying cry. 

"She was warned," McConnell said. "She was given an explanation. Nevertheless, she persisted."

On Thursday the Senate will debate Rep. Tom Price, the nominee for Health and Human Services secretary.

Sessions will be confirmed on Thursday.

Information from the Associated Press contributed to this report.